The influence of aminopterin on limb regeneration in Ambystoma mexicanum.
نویسندگان
چکیده
منابع مشابه
Comparison of the effects of vitamin A on limb development and regeneration in the axolotl, Ambystoma mexicanum.
The objective of this investigation was to compare the effect of vitamin A on limb development and limb regeneration in the same animal, at the same time, thus eliminating the possibility that species differences or different rates of uptake between animals would influence the results. Axolotl larvae had both right limbs amputated and then were treated with retinol palmitate by immersion at 60 ...
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Multiple factors are thought to cause limb abnormalities in amphibian populations by altering processes of limb development and regeneration. We examined adult and juvenile axolotls (Ambystoma mexicanum) in the Ambystoma Genetic Stock Center (AGSC) for limb and digit abnormalities to investigate the probability of normal regeneration after bite injury. We observed that 80% of larval salamanders...
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The data presented in this article are related to the article entitled "Cartilage and bone cells do not participate in skeletal regeneration in Ambystoma mexicanum limbs" [1]. Here we present image data of the post-embryonic development of the forelimb skeletal tissue of Ambystoma Mexicanum. Histological staining was performed on sections from the intact limbs of young (6.5 cm) and old (25 cm) ...
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The Mexican axolotl, Ambystoma mexicanum, is a unique vertebrate species which has amazing powers of limb regeneration. In the present study we have used a Subtractive Amplification approach to identify genes which are activated and overexpressed during the limb regeneration process. In our initial studies, we have found that levels of expression of 11 genes are increased during the limb regene...
متن کاملChemical activation of Wnt/β-catenin signalling inhibits innervation and causes skeletal tissue malformations during axolotl limb regeneration
Limb regeneration involves several interrelated physiological processes in which a particular signalling pathway may play a variety of functions. Blocking the function of Wnt/β-catenin signalling during limb regeneration inhibits regeneration in axolotls (Ambystoma mexicanum). Limb development shares many features with limb regeneration, and Wnt/β-catenin activation has different effects depend...
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عنوان ژورنال:
- Journal of embryology and experimental morphology
دوره 16 1 شماره
صفحات -
تاریخ انتشار 1966